Methylsulfonyl Methane (MSM)

MSM is an abbreviation for a naturally occurring compound called methylsulfonylmethane or dimethylsulfone (DMSO2). MSM is a significant source of the element, sulfur, accounting for nearly 34 percent of its entire weight. [1] MSM appears as a white crystalline powder and despite being relatively high in sulfur, MSM has no odor. The compound DMSO is chemically related with MSM; being synthesized via oxidation.

The exact mechanism of action for MSM is not fully known. However, MSM does exhibit mild anti-inflammatory and antioxidant activities which may account for many of its clinical effects. [2] MSM is easily absorbed and enters the bloodstream within hours of consumption. [3] MSM has demonstrated the ability to cross the blood-brain-barrier as evidenced by magnetic resonance spectroscopy (MRS). [4]

may play a role in cancer prevention. MSM has specific effects on cellular proliferation and appears to function in a manner similar to aspirin. A study showed that MSM, when combined with aspirin, induced differentiation by a COX-independent mechanism. [5] The authors suggest that a common mechanism for the chemopreventive action might be the activation of gene functions, leading to differentiation and thereby dismantling the cellular capacity for proliferation.

Products Containing Methylsulfonyl Methane (MSM)
Name Price Rating Serving Price # of Servings Manufacturer Health Condition
Animal Flex $23.44
$0.53 44 Universal Nutrition Osteoarthritis
Exomine RH $54.95
$1.83 30 Progressive Health


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