MSM (Methyl-Sulfonyl-Methane)

MSM is an abbreviation for a naturally occurring compound called methylsulfonylmethane or dimethylsulfone (DMSO2). MSM is a significant source of the element, sulfur, accounting for nearly 34 percent of its entire weight. [1] MSM appears as a white crystalline powder and despite being relatively high in sulfur, MSM has no odor. The compound DMSO is chemically related with MSM; being synthesized via oxidation.

The exact mechanism of action for MSM is not fully known. However, MSM does exhibit mild anti-inflammatory and antioxidant activities which may account for many of its clinical effects. [2] MSM is easily absorbed and enters the bloodstream within hours of consumption. [3] MSM has demonstrated the ability to cross the blood-brain-barrier as evidenced by magnetic resonance spectroscopy (MRS). [4]

may play a role in cancer prevention. MSM has specific effects on cellular proliferation and appears to function in a manner similar to aspirin. A study showed that MSM, when combined with aspirin, induced differentiation by a COX-independent mechanism. [5] The authors suggest that a common mechanism for the chemopreventive action might be the activation of gene functions, leading to differentiation and thereby dismantling the cellular capacity for proliferation.

Products Containing MSM (Methyl-Sulfonyl-Methane)
Name Price Rating Serving Price # of Servings Manufacturer Health Condition
Bone Boost $21.97
$1.10 20 SAN
Cytoflex Hyaluronic Acid Gel $10.70
$0.00 0 Cytosport
Glucosamine & Chondroitin Plus MSM $21.89
$0.36 60 NOW Osteoarthritis
Joint Repair $12.95
$0.43 30 Dymatize Osteoarthritis
Joint Synergy Roll-On $6.59
$0.22 30 MRM
Joint Synergy+ $7.29
$0.24 30 MRM
Neoflex $19.95
$0.66 30 Vitamin Health Inc Osteoarthritis
Phosoplex $49.99
$1.67 30 Optimal Therapeutics Osteoarthritis
Proflex Joint Support $12.75
$0.42 30 Champion Osteoarthritis
Xmotion $34.95
$1.17 30 Xyience


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