ISS' ZMA - Product Review  Hot



ISS' ZMA features an all-natural, non-steroidal mineral formula scientifically shown to boost testosterone and muscle strength. This anabolic (muscle building) formulation contains highly bioavailable forms of the minerals zinc monomethionine aspartate and covalently-bound zinc/magnesium aspartate, as well as vitamin B-6. Studies suggest that ZMA can increase free testosterone levels, IGF-1 (insulin-like growth factor) and muscle strength in athletes.

Magnesium and zinc are minerals used to support testosterone production and promote sleep. This combination of minerals promotes deep sleep, when the body's hormonal production is maximized. The addition of vitamin B6 further enhances zinc and magnesium absorption and utilization. ZMA helps increase IGF-1 levels, which promotes muscle strength during workouts. Studies suggest that athletes' zinc and magnesium levels can significantly decrease after participating in regular intense workouts and performance. This mineral depletion is associated with a decline in muscle endurance or total work capacity.

In one study, published in Medicine and Science in Sports and Exercise, researchers administered either ZMA or a placebo (fake supplement) to NCAA football players daily during an eight-week spring training program. Pre and post leg strength measurements were made using a Biodex isokinetic dynamometer. Researchers found that the ZMA group had an 11.6% strength increase, compared to a 4.6% increase in the placebo group. The ZMA group also had a 30% increase in free and total testosterone levels compared to a 10% decrease in the placebo group. Furthermore, the ZMA group had a small increase in IGF-1 levels compared to a 20 percent decrease in the placebo group.


ZMA is scientifically shown to increase testosterone levels, muscle strength and IGF-1.

ZMA has the following benefits:

  • All-natural, non-steroidal testosterone booster for men and women
  • Increases free testosterone levels
  • Enhances IGF-1 levels
  • Promotes muscle strength gains during training


People with pre-existing medical conditions or taking medication should not supplement with ZMA without consulting a physician.

Be aware that some drugs may interact with the nutrients in ZMA including:

  • Alendronate
  • Amiloride
  • Amphotericin B
  • Azthromycin
  • Azt
  • Benazepril
  • Benzamycin
  • Bile acid sequestrants
  • Cimetidine
  • Ciproloxacin
  • Cisplatin
  • Cycloserine
  • Cyclosporine
  • Calcium acetate
  • Captopril
  • Chemotherapy
  • Chlorhexidine
  • Cindamycin topical
  • Colestipol
  • Cyclophosphamide
  • Docetaxel
  • Doxycline
  • Digoxin
  • Docusate
  • Doxycycline
  • Erythromycin
  • Estrogens (combined)
  • Folic acid
  • Famotidine
  • Felopidine
  • Fentanyl
  • Gemifloxacin
  • Gentamicin
  • Gimepride
  • Glipizide
  • Hydroxychloroquine
  • Isoniazid
  • Levofloxacin
  • Loop Diuretics
  • Lisinopril
  • Lotrel
  • Medroxyprogesterone
  • Metformin
  • Minocycline
  • Misoprostol
  • Mixed amphetamines
  • Methotrexate
  • Methyltestosterone
  • Metronidazole (vaginal)
  • Neomycin
  • Nitrofurantoin
  • Nizatidine
  • Ofloxacin
  • Oral contraceptives
  • Oral corticoseroids
  • Ofloxacin
  • Penicillamine
  • Quinidine
  • Quinolones
  • Quinapril
  • Ramipril
  • Risedronate
  • Sotalol
  • Spironolactone
  • Sulfamethoxazole
  • Sodium fluoride
  • Topical corticosteroids
  • Tetracycline
  • Theophylline/aminophylline
  • Thiazide diuretics
  • Tobramycin
  • Triamterene
  • Trimethoprim
  • Valproic acid
  • Warfarin

Is it for you?

If you're a male or female athlete looking for a clinically studied anabolic mineral support formula, ZMA is for you.

However, people with pre-existing medical conditions or taking medication should not supplement with ZMA without consulting a physician.

Dosage and Directions

Men take 3 (women take 2) capsules daily, preferably on an empty stomach 30 to 60 minutes before bedtime.

For best results, avoid taking with dairy or other calcium-containing foods or supplements.

Store in a dry, cool place.

ZMA for Testosterone Supplement Facts

Serving Size: 3 Capsules
Servings Per Container: 30
  Amount Per Serving Daily Value
Manganese (from Manganese Aspartate) 450 mg 113% (4618)
Zinc (as /-Monomethionine and Aspartate) 30 mg 200% (6804)
*percent Daily Values are based on a 2,000 calorie diet.

Ingredients: Other Ingredients: Gelatin, Magnesium Stearate.

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