Chondroitin Complex

Chondroitin sulphate is a molecule made of sugars and amino acids. It exists within the category of metabolically active molecules known as glycosaminoglycans (GAGs). At one time these substances were commonly referred to as mucopolysaccharides. Glycosaminoglycans comprise the ground substance or “filler” in the extracellular matrix of collagen. In humans GAGs can be found in cartilage, bone, cornea, skin and the walls of large arteries.

There are four different structural varieties (isomers) of chondroitin sulphate, and each is dependent upon the arrangement of the sugars and amino acids. They are labeled A, B, C, and D; with chondroitin sulphate A being the most abundant in human biology. Most supplements contain a mixture of A and C, which are the most abundant forms found in shark and whale cartilage products. However, small amounts can also be found naturally in humans. The different isomers have different molecular weights, and those with lower weights are more readily absorbed and integrated into tissues.

Chondroitin sulphate
is absorbed in the stomach and small intestine. Once absorbed, chondroitin sulphate has been shown to enter the joint space, with a tropism, or affinity for the knee joint. However some of the chondroitin sulphate is digested and broken down to glucosamine, which is also a (GAG) and serves the same purpose.

Chondroitin sulphate's
main function is to maintain structural integrity and function of cartilage. It can also be used to relieve pain in musculoskeletal disorders such as osteoarthritis (OA). It has also shown some mild anti-inflammatory activity. Although the exact mechanism of action is not completely understood, studies have determined that supplemental chondroitin sulphate does, in fact, enter the joint spaces (cavities).

Products Containing Chondroitin Complex
Name Price Rating Serving Price # of Servings Manufacturer Health Condition
Joint Synergy Roll-On $6.59
$0.22 30 MRM
Joint Synergy+ $7.29
$0.24 30 MRM


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