N-acetyl-cysteine (NAC)
NAC is useful for
an adjunctive treatment for both acute
and chronic sinusitis. It is a mucolytic, meaning it breaks up
mucous. It is equally helpful
for encouraging
drainage of the sinus. NAC is also
an effective antioxidant and has been shown to
possess some anti-viral activity. It is not
habit forming, and does not cause
any side effects. In one
study NAC was proven an effective
adjunctive treatment to help clear
mucous and drain the sinuses.
Furthermore, NAC prevented chronic sinusitis in
children in 98.5% of the cases. [5]
Bromelain
Bromelain is a
plant enzyme from pineapple. It is
both a mucolytic and fibrinolytic.
Bromelain is also purported to have immune modulating
activity. It is anti-inflammatory
and anti-edematous, making it very useful for
sinusitis. Bromelain is a natural substance and
is non-toxic. There are no
known side effects associated with
the supplementation of this enzyme. [6]
Antioxidants
Antioxidant
supplementation is beneficial in
many disease processes. Antioxidants play a role in the
functioning of the immune system and
are an integral component in our
body's natural defense processes against
microorganisms. Additionally,
when tissues
are inflamed, oxidative stress is
increased. This oxidation is,
largely, due to the formation of
reactive oxygen species and free
radicals by the microorganisms and
our bodies own defenses.
Antioxidant levels were found to be
decreased in the nasal tissue of
individuals suffering from chronic
sinusitis. Antioxidant supplementation should
be an adjunctive treatment for any
case of sinusitis and that
supplementation may bring a better
prognosis to the course of the
infection. [7] Antioxidants that may be helpful
include Vitamins A and C, and
the mineral, Selenium.
Botanical sinusitis
treatments:
Historically, many botanical
medicines have been
used in the treatment of acute and
chronic sinusitis. The biggest
problem in botanical medicine is that not a lot of
research has been done with applying a
particular herb to a particular
disease process. Instead, what
research has been done explores only the
activities of certain botanicals. That documented research
then allows the medicine to be
applied to certain conditions based
on its physiological actions.
Sambucas,
elderberry
Elderberry has
historically been used for sinusitis,
as well as a medicine to prevent
recurrent sinusitis from an upper
respiratory infection (e.g. cold, pharyngitis). In
one particular study, elderberry
was shown to be antiviral,
protecting against
influenza A and B, which are common
agents that contribute to the
development of sinusitis. Individuals in this study had a
resolution of symptoms 4 days sooner
than individuals in the control
group. This study's participants
had no need for the use of stronger medications
like antibiotics to resolve the
sinusitis. [8]
Andrographis
paniculata
Andrographis is an
immunomodulating herb. It enhances
the immune system, or provides
support to the immune system.
In the past, this herb has been used as a
common
treatment for sinusitis. In
one study, symptoms of sinusitis such
as fever, headache, malaise, sore
throat, cough, and nasal discharge
all improved in participants over
controls. Andrographis was
also shown to exhibit anti-inflammatory action in
individuals with sinusitis. [9]
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