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Conventional treatment of rosacea is focused on topical or oral antibiotics. The most common topical antibiotic treatments are 0.75% Metronidazole cream and erythromycin gel. Commonly prescribed forms of oral antibiotics include tetracycline and doxycycline. Patients with later stage disease that do not respond to antibiotics can be treated with oral isotretinoin (a vitamin A product). Surgery may also be recommended in cases of severe overgrowth of the nose. [5]

 

There very few alternative recommendations outlined in medical literature for the treatment of rosacea. Although, it has been suggested that rosacea's treatment with nutraceuticals should focus on repairing the integrity of the skin and reducing inflammation in the individual. Again, the exact antecedent in the development of this condition is unknown, however, treatment options can also be directed at the hypothetical cause(s) for rosacea.

 

 

Supplements helpful for Rosacea

 

Azelaic acid

Azelaic acid is a naturally occurring substance. It is thought to possess certain antibiotic and anti-inflammatory properties. Azelaic acid has been proven effective in clinical studies at treating papulo-pustular rosacea, though no positive effect has been demonstrated on telangiectasia (blood vessels). In one study, a 15% azelaic acid cream was demonstrated to be as effective as 0.75% metronidazole gel at reducing redness, papules, and pustules. [6] In another double-blind study a 20% azelaic acid cream was compared to placebo. Those persons administered azelaic acid had significant decreases in lesions and redness. The only reported side effect was mild burning after application, which typically resolved after several applications. [7]

 

NADH

NADH is a biochemically active form of nicotinamide (Vitamin B3). It is used in energy metabolism (the production of ATP). It is also a potent anti-oxidant. NADH protects the integrity of cellular membranes located throughout the body from damage by free radicals. In one particular study, a 1% NADH ointment was applied daily to affected areas in individuals with rosacea. These patients had significant improvement in their overall symptoms with no accompanying side effects. [8] The result of this study may show NADH as a relevant topical treatment for rosacea, as compared to other notable topical applications.

 

Vitamin C

Vitamin C is one of the most potent and active anti-oxidants in the body. Being nutritive to the skin, it also promotes tissue integrity and tissue healing. Damage from free radicals may play a role in the development of rosacea. Vitamin C can be used both topically and orally for the treatment of rosacea. One study found that daily use of a 5% vitamin C (ascorbic acid) preparation reduced erythema (redness) in 75% of the participants with rosacea. [9]

 

Vitamin A

Vitamin A is another essential nutrient for skin health. It promotes cellular integrity and healing to epithelial cells (skin). Vitamin A is also considered a potent anti-oxidant, and anti-inflammatory agent. Studies conducted on this vitamin have shown this fat-soluble vitamin to be effective at treating rosacea. [10,11] This is thought to be caused by its anti-oxidant capabilities and the protective effects it exerts on skin cells.

 

Essential Fatty Acids

Essential fatty acids are anti-inflammatory in nature. Proper intake of omega 3 and omega 6 fatty acids will inhibit production of pro-inflammatory molecules. This may provide a significantly beneficial effect for individuals with rosacea because the condition is a chronic inflammatory disorder of the skin. Supplementing with essential fatty acids is also beneficial for the skin, as the constituents of these oils improves the integrity of the cell membranes. Sources of omega 3 fatty acids, include fish oils, flaxseed oil, and black currant seed oil. Sources of omega 6 fatty acids are borage oil, evening primrose oil, and sunflower oil.


 

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