Vitamin C
The importance of
vitamin C for periodontal health
is documented by the effects in a
nutritional deficiency syndrome of
this vitamin, called scurvy. As
mentioned above, scurvy can cause
swelling of the gingiva and
subsequent infections. If a patient has this
condition, vitamin
C therapy is indicated.
Furthermore, vitamin C helps
prevent and treat periodontitis
by increasing gingival praline and
hydroxyproline content, increases
mucopolysaccharide synthesis,
reduces subsequent bacterial
invasion, and decreases gingival
bleeding. [8]
Clinical research has shown that
patients with low levels of
vitamin C are predisposed to early
stage gingivitis. [9] Periodontal disease in patients
with the genetic disorder, Chediak-Higashi
syndrome, has been effectively
treated with vitamin C therapy. [10]
Folic acid
Folic acid is an
important nutrient to consider for
the treatment of periodontal
disease. Numerous studies have
shown that using folic acid in the
form of either mouth rinse or pill has been effective in periodontitis
treatments. [11-13] One study
specifically showed that gingival inflammation was reduced
when subjects used a folic acid
mouth rinse.
Sanguinaria
canadensis (Bloodroot)
Sanguinaria
canadensisis
an herb found in the Appalachian
Mountains in the eastern United
States. The root of this plant
contains certain constituents that
have medicinal activity. The
primary active constituent in this herb is
sanguinarine, and has shown
effectiveness as a mouth rinse. [14]
In one study, adult
patients with periodontal disease
who received a toothpaste and
mouth rinse containing Sangiunaria extract had
significantly fewer bleeding sites
at subsequent dental
examinations. [15] Another study showed that Sanguinaria can actually
inhibit the ability of bacteria to
adhere, thus preventing plaque
formation. [16]
Flavonoids
Flavonoids are
compounds found in colored fruits
and vegetables that assist with
collagen stabilization. Flavonoids
also synergize the effects of
vitamin C, and could be
taken to augment the effect of
vitamin C noted in the section
above. Specific effects of flavonoids in periodontal health
include, decreasing membrane
permeability, inhibition of mast
cell degranulation, and the cross-linking
of collagen fibers. These
processes ultimately inhibit
the destruction of collagen, a
common characteristic of periodontitis. [17,
18] In addition, specific flavonoids
have demonstrated in animal study to delay the growth
of plaque and alveolar bone resorption. [19]
CoEnzyme Q10
This nutrient has
demonstrated effectiveness for the
treatment of periodontal disease
in a placebo-controlled double
blind study. Patients took
either Coenzyme Q10 or placebo
over a 3 week duration. [20] The patients taking
CoQ10
showed improvements in pocket
depth, purulent exudates, tooth
mobility, gingival swelling,
bleeding, redness, pain, and
itching.
|
Learn More About
Periodontal Disease |