Zinc
Zinc is an
essential mineral for metabolism
of the retina. It is often
deficient in elderly patients.
Low intake of zinc is associated
with an increased risk for age
related macular degeneration. [9]
In the large Age Related Eye
Disease Study (AREDS) zinc use was
associated with a decreased rate
of mortality in patients with
macular degeneration. It
was also found to be an integral
aspect of treatment with
antioxidants to prevent advanced
stage macular degeneration. [10]
Copper
Copper is a
necessary addition to the
treatment regimen for macular
degeneration, to offset the
adverse reactions associated with
high doses of zinc.
Supplementation with high doses of
zinc can cause reflex copper
deficiency, which can result in
anemia. Copper must be
supplemented to avoid this side
effect. [11]
Vitamin E
Vitamin E is an
antioxidant. It is present
in large amounts in the retina.
Vitamin E is the most abundant
fat-soluble antioxidant in the
retina. Studies have shown
Vitamin E to be protective against
the development of macular
degeneration. [12]
One study found that
supplementation with Vitamin E
reduced the risk of macular
degeneration by as much as 13%. [13]
Vitamin E was also a piece of the
antioxidant formulation used in
the AREDS study that found its
supplementation prevented advanced
stages of macular degeneration. [14]
Vitamin C
Vitamin C is a
potent antioxidant. It is
present in high amounts in the
retina, and functions along side
Vitamin E in preventing free
radical damage to the eyes.
Vitamin C is a protective
nutrient, and is used by the
retina for preventing damage
caused by sunlight. Vitamin
C was included in the antioxidant
formula in the large AREDS study.
It was shown to prevent the
development of advanced macular
degeneration.
Beta-carotene
Beta-carotene is
essential for proper function of
the retina. It is present in
high amounts in the pigmented
cells of both the retina and
macula. Beta-carotene was
found to be effective at
preventing the advanced stage of
macular degeneration in
the AREDS study. {15]
Lutein
Lutein is a
carotenoid. It is present in high
amounts in the pigmented cells of
the macula. Lutein is
protective against the damage
caused by sunlight. Medium
to high intake of lutein is
associated with a decreased risk
of developing macular
degeneration. [16]
Ginkgo biloba
Ginkgo is a
botanical antioxidant that has
been shown to improve blood flow
to the eyes. It is also
considered anti-atherogenic.
Ginkgo has been proven in studies
to improve visual acuity in
patients with macular
degeneration. [17]
This improvement is thought to be
due to its potent antioxidant
effects.
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