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Gout Treatment

 

Standard conventional gout treatments rely upon the use of non-steroidal anti-inflammatory (NSAIDs) drugs or the use of colchicines.  Colchicine is derived from the autumn crocus plant and certain constituents in this plant can help with the inflammatory process.  Over 75% of patients show major improvement in symptoms within 12 hours of ingesting these medications.  However, colchicines tend to cause major gastrointestinal side-effects such as nausea, vomiting, diarrhea, and abdominal pain. [5, 6]  Colchicines may also cause bone marrow depression, hair loss, liver damage, seizures and even death.

 

 NSAIDs, such as indomethacin, are also used to treat acute gouty arthritis.  It is generally the preferred treatment in causes of standard diagnosed gout, and is prescribed at the typical dosage of 25 mg/day.  NSAIDs are often the cause of gastrointestinal bleeding and ulceration.  These type of prescriptions should be used with medical supervision and extreme precaution because of the likelihood of adverse side effects.

 

 

Supplements helpful for Gout

 

Diet:
 

A healthy diet and body weight is one of the most important factors in preventing and treating gout.  Obesity is probably the most important factor that contributes to the onset of this condition. [7]  Healthy weight loss should be a goal for every patient with gout. [8]  Foods with high purine levels should be avoided, such as organ meats, shellfish, and certain types of fish, like sardines and anchovies.  Homogenized milk should also be avoided due to its tendency to increase uric acid levels. [9]  Adequate amounts of protein should be ingested, but should not be excessive.  Foods that should be added to one's diet may include; black cherries, purple grapes, raspberries, blackberries and strawberries. [10]  Certain fats, such as those found in fish, flax or olive oil, may also have some anti-inflammatory effects and should also be consumed. Adequate hydration is also important.  In addition, there should be an avoidance of beverages that contain both alcohol and caffeine.

 

Vitamins and Nutrients:

 

Vitamin E
800 IUs of Vitamin E per day inhibits some of the inflammatory pathways associated with gout and also acts as a potent antioxidant.  Selenium, another antioxidant, acts synergistically with vitamin E, and these nutrients should be taken together.

 

Folic acid
High levels, up to 10-40 mg/day, of folic acid may be used to help diminish the enzyme responsible for producing uric acid. [
11]  These high doses may interfere with some drugs that are used for epilepsy.  Caution should be used.

 

Omega-3 oils

This essential fatty acid helps to decrease the inflammation and joint damage that may occur in gout sufferers.  Flax seed oil and fish oil are extremely important to help with inflammation.  Levels of eicosapentaenoic acid (EPA) should be approximately 1.8 gm/day.

 

Avoidance of high levels of vitamin C and niacin- may increase uric acid in some patients. [12]  Niacin competes with uric acid in excretion and may contribute to levels which are higher than normal.

 

Botanicals:

 

Bromelain
Bromelain is an enzyme derived from the pineapple and is a potent anti-inflammatory agent and analgesic.  It should be taken between meals on an empty stomach. [
13]

 

Quercetin
This bioflavanoid may inhibit the enzyme xanthine oxidase, as well as the drug allopurinol.  It should be taken with Bromelain between meals, since the Bromelain will help enhance absorption.

 

Devil's claw
Harpagophytum procumbens has been used for many sorts of arthritis in the past. [
14] Research has shown it to be a potential treatment for gout by reducing serum uric acid levels.  It also lowers serum cholesterol levels.
 

 

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