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Treatments options, routinely selected for
Endometriosis, are
considered dependant upon
the extent the disease. Relatively mild Endometriosis is
usually not treated. Instead, physicians may suggest using
over-the-counter pain relievers or
prostaglandin inhibitors (e.g. ibruprofen, naproxen,
acetaminophen) for the
management of pain. In some
cases, typically when patients
wish to become pregnant, hormonal
agents such as birth control
pills may be utilized.
For
women who are not seeking a
pregnancy and have received a
definitive diagnosis, various hormonal
suppression therapies are used to
end ovulation. These may
include;
-
Androgens: male sex
hormones, like Danazol
-
GnRH agonists:
gonadotropin-releasing hormone
agonists, which block pituitary
gland hormones that normally
stimulate ovarian cycles
-
Combination Therapies:
ex: estrogen taken in combination with
an Oral contraceptive
Hormone
treatment is successful in nearly
80 - 90 percent of patients with
smaller endometrial implants.
However, this form of treatment is
often questioned because of the
many safety issues concerning male
hormones being used in women, as
well as other adverse side effects
(e.g. loss of bone mineral
density); all of which are of
increasing concern when using this
particular treatment protocol.
In the severest
cases of Endometriosis,
'conservative' surgery is
recommended to remove the diseased
tissue. The surgical
excision or cauterization of endometrial
lesion(s) is done via laparoscopy
or laparotomy. Laraoscopy
treatments are considered feasible
when the surgeon can see pelvic
structures clearly through a
laparoscope. Newer
techniques, such as laser
vaporization are also currently
being employed, and provide
substantial reductions in patient
recovery times. [6]
- Other
Standard Approaches in
Endometriosis Treatment
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Nutritional: |
Dietary: |
Physical: |
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Vitamins |
Avoiding specific
food and environmental toxins |
Movement /
Exercise |
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Minerals |
Consumption of
more immune-stimulating foods |
Increased Muscle
Tone |
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Amino Acid /
Proteins |
Consumption of
foods containing natural plant
sterols (phytosterols) |
Increased Aerobic
Capacity |
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Essential Fatty
Acids |
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Breathing
Techniques |
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Antioxidants |
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Postural
Adjustments |
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Nutrient and
Herbal Supplements |
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Enzymes |
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Homeopathic
Remedies |
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Supplements helpful for
Endometriosis |
Vitamins and Minerals:
Vitamin C
Vitamin C is a well known
antioxidant vitamin that is
found primarily in fruits and
vegetables. Humans are among the
few mammals that are unable to
produce their own vitamin C and
must obtain it from various
dietary sources. High doses of vitamin
C have been shown to improve
autoimmunity s well as to decrease the
inflammatory reactions. [8,
9]
Beta Carotene
Beta
Carotene is in the same class of
compounds as vitamin A. Approximately one third of the
beta carotene in the diet is
converted into Vitamin A. Oral
supplementation with
beta-carotene has been shown to
increase the number of T4 immune
cells that can help to prevent
and lessen autoimmune reactions. There is also evidence that
various carotenoid compounds,
including beta-carotene, are
capable of inhibiting some tumor
formation. Additionally, NK cell
numbers and activity have been
observed to be increased in
response to beta-carotene
supplementation, possibly
resulting from the anti
carcinogenic effects of carotenoids.
[10,
11,
12]
Vitamin E
Vitamin E is another antioxidant
nutrient that is important for
the proper function of many body systems including the
immune system. Vitamin E can
also modify ratios of
Progesterone to estradiol
towards a more normal ratio.
This is significant as many gynecological conditions,
including Endometriosis, which
are
associated with a progesterone
to estradiol ratio that is too
low. Dysmenorrhea is the
most common
symptom of Endometriosis,
and is often the indicator that
brings women to see their
physician. Vitamin E is an
effective way to help diminish
the symptoms of Dysmenorrhea by
regulating estrogen metabolism
and certain inflammatory
processes. [13,
14]
Selenium
Selenium is a mineral that is
involved in a number of
detoxification and antioxidant
reactions. Selenium is also
important for proper function of
the immune system. Selenium has
demonstrated an ability to
enhance both B and T cell
function and proliferation.
A greater immune response has
been
observed in subjects that have
been treated with Selenium than
in controls. Selenium also
stimulates a greater cell
mediated response to malignant
cells and may reduce tumor
formation. When taken with
Vitamin E, selenium has also
been shown to positively impact
immune response. In
addition, this mineral is
critical for fatty acid
metabolism. Due to the fact that
Endometriosis involves cells
developing ectopically, it
suggested that this type of support
for the immune system is
beneficial. [15,
16,
17]
Other
Nutritional and Dietary
Supplements:
Essential
Fatty Acids
Essential Fatty Acids (EFAs) are
a class of compounds that are
found in various natural sources, such as
flax seed, borage seed,
hemp seed, and cold water fish
body oils. Other fatty acids
that are
present in diet are regularly acquired form
terrestrial animal sources, like beef, poultry,
etc. The fatty acids that are
acquired from animal sources
tend to lead to the formation of
pro-inflammatory compounds in
the body (Prostaglandins), while EFAs lead to the formation of
less inflammatory compounds. Due
to the inflammatory nature of
Endometriosis, it is thought
that limiting inflammatory
conditions in the body would be
of benefit in this condition. [18]
Lipotropics
Lipotropics are compounds that
function as cofactors in the
Liver's role of detoxification. Normally hormones are
metabolized in the liver into
less active forms and are
then eliminated from the body. It is
possible that an imbalance of
hormonal levels can contribute
to the pathogenesis and
progression of Endometriosis.
Supplementation with lipotropic
compounds will ensure that the
liver has the materials it needs
to do its job of hormonal
elimination. [19]
Lipotropic combinations often
times include the amino acids
methionine, choline, and
inositol, which facilitate the
transportation of fats out of
the liver. Specific herbs,
such as milk thistle, dandelion, tumeric, boldo,
are also added to lipotropic
formulas. These herbs are
known to stimulate gallbladder
function, increase secretions of
bile, and cleanse the body;
characteristics deemed
beneficial for improving the
symptoms associated with
Endometriosis.
Black Cohosh
Root:
Black Cohosh Root
contains many active
constituents, including the
isoflavone most beneficial to
women, formononetin.
Formononetin, along with other
compounds found within the root,
actually bind to estrogen
receptors of the uterus.
This may prove
especially relevant for women
suffering from Endometriosis.
Certain phyto-estrogens block
estrogen from binding at uterine
receptor sites, thereby
lessening the overall symptoms
of the condition. In fact,
several studies have reported
that Black Cohosh has positive
menopausal and post-menopausal
effects, which may be extremely
beneficial for women suffering
from Endometriosis. [20,
21]
Saw Palmetto /
Saw Palmetto Extract:
Saw Palmetto is a
traditional treatment for
supporting prostate health in
men. However, recent study
has revealed that it can
actually block the action of the
sex hormone, Follicle
Stimulating Hormone (FSH).
This finding may prove
significant in women suffering
from Endometriosis, as FSH has
been shown to increase
endometrial tissue in study.
Dietary supplementation with Saw
Palmetto-containing products may
work to reverse or eliminate
this effect.
Chasteberry
and Dong Quai:
Chasteberry (also
commonly referred to Vitex)
and Dong Quai are herbs that are
traditionally combined together
to assist in the balancing of
hormones in Endometriosis
sufferers. For treatment,
these herbs are taken daily and
are recommended to be
administered over the duration
of a three to six month period.
. The balancing of
hormones remains integral in
Endometriosis, as certain
hormones may actually work to
promote the spreading of
endometrial tissue and result in
increases of endometrial pain.
Some nutritionist also suggest
using wild yam in
addition to this synergistic
combination to provide a
reduction in possible cramping
and to also soothe the uterus. [22]
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