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Standard
treatment for Emphysema
involves numerous components, many
of which aim at treating the
various sequelae that can come
from Chronic Obstructive Pulmonary
Diseases. Smoking cessation is
first and foremost important
action in
the treatment of Emphysema.
Setting a quit date, the
application of transdermal
nicotine patches, and behavioral
therapy are all useful strategies
for attaining the goal of quitting
the use of tobacco. Patients with Emphysema are
considered to be in a high risk
group for purposes of influenza
infection and should receive a flu
vaccination every year. A pneumococcal vaccine should also
be considered.
Pharmacological treatments for
Emphysema are aimed at
alleviating symptoms and may include; bronchodialators and oxygen to
improve shortness of breath,
Theophylline to reduce spasms,
and antibiotics can help prevent
and treat lung infections that can
be common in patients with Chronic
Obstructive Pulmonary Diseases. [5]
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Supplements helpful for Emphysema |
N-Acetyl
Cysteine
N-
acetyl Cysteine serves as the
precursor for glutathione, which
is one of the main antioxidants
in the body and is vital for
health. N-Acetyl Cysteine is
more stable and readily absorbed by the
body than the amino acid it is
derived from-cysteine.
In
the treatment of Emphysema,
N-Acetyl Cysteine can serve a
number of purposes. It can act
as a direct scavenger of
reactive oxygen species that
have been implicated in the
pathogenesis of Emphysema. N-Acetyl Cysteine
also serves as the
precursor for Glutathione (see
below), and also has the
effect of thinning mucus
secretions that are often
prevalent in Chronic Obstructive
Pulmonary Diseases. N-acetyl Cysteine has been demonstrated
to be effective in protecting
lung tissue from damage induced
by environmental insults such as
cigarette smoke. The beneficial
effects of N-acetyl Cysteine
appear to be enhanced by
the concurrent use of a selenium-containing heterocycle
compound. [6,
7,
8]
Glutathione
Glutathione is an antioxidant
compound that is composed of 3
amino acids: cysteine,
glutamine, and glycine. Glutathione is one of the main
antioxidants that occurs in the
body and is used to prevent
damage to both cell membranes
and genetic material. Glutathione
also functions to help keep
other antioxidant systems in a
reduced state so that they can
perform their protective
antioxidant functions. It is
believed that high glutathione
levels may protect lung tissues
from the damaging effects of
cigarette smoke on alveolar
macrophages.
The
availability of glutathione that
is taken orally is uncertain and
it is considered more available
in a nebulized form. For this
reason, it is considered more
effective
to take the precursor to
glutathione, N-acetyl cysteine,
orally. In the pathogenesis of
Emphysema there seems to be and
imbalance between oxidants and
antioxidants in the lung
tissues. This imbalance is
exacerbated by environmental
insults such as cigarette smoke
and air pollution. Nebulized
Glutathione has been
successfully used to avert an
acute respiratory crisis caused
by Emphysema. It has also
been shown to improve
the course of the chronic
disease process. [10,
11,
12]
Other
Antioxidants
In
imbalance of oxidants and
antioxidants in the lung tissues
is one of the major factors that
can contribute to the
pathogenesis of Emphysema. It
has been demonstrated that
exposure to both primary and
secondary cigarette smoke
increases the oxidative stress
that is placed on lung tissues. Even though the lungs are
considered an internal organ, they are constantly exposed to
the outside environment in the
form of the gases that are
introduced to the lung with
every breath.
The
lungs are equipped with numerous
defenses to prevent damage to
their sensitive tissues. Among
the lungs' defenses are
antioxidant systems that serve
to protect the various cells in
the lungs from damage. When the
antioxidant defenses are
overwhelmed, the "door" is
then opened for development of
such diseases as
Emphysema. It is
important to ensure that the
balance of antioxidants to
oxidants remains high in the
lungs to help improve lung
condition and prevent further
damage. [14,
15,
16,
18]
Usage: Emphysema treatment should
include a
multivitamin that contains
adequate doses of antioxidant
vitamins including; Vitamin E,
Vitamin C, Copper, Zinc,
beta-carotene (only after
smoking cessation has been
achieved), Selenium, and
Manganese.
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