Essential Fatty acids
Essential fatty acids are
represented by the omega-3 and 6
Fatty acids. Sources of omega 3
fatty acids include; flax, hemp,
canola, fish and walnut oils. Sources of Omega 6 include;: corn,
canola, safflower, soy and
sunflower oils. In the body,
essential fatty acids are
incorporated into cell membranes
and contribute to the physical
characteristics thereof. It is
these fatty acids that are
liberated from the membrane (via
the enzyme Phospholipase) and used
to make many compounds, including thromboxanes, leukotrienes, and
prostaglandins. These compounds
are responsible for beginning and
controlling the inflammation
response.
The fatty acids that are
derived from grain fed animal
sources (called Arachadonic acid), as well as those that are damaged
by processing such as
hydrogenation (ie to make
margarine), tend to lead to the
formation of more pro-inflammatory
series of prostaglandins. When
adequate omega-3 fatty acids are
available, the compounds that are
derived from them are much less
inflammatory and will lead to less
symptoms of inflammation in
disease conditions, such as eczema. [10] Evening
primrose oil is a source of
essential fatty acids and has also
been found to be effective in
lessening the symptoms of eczema,
including itching. Although this
can be an expensive treatment
choice and is not always effection
in eczema sufferer. [11]
Zinc
Zinc
is an important nutrient for skin
health and is necessary for the
function of enzymes that help to
utilize EFAs. Essential
fatty acids must undergo numerous
biochemical changes before they
can be used in the body's
processes, regardless of their
availability in the human body. If there is a
deficiency with Zinc, Magnesium,
or Vitamin B6, the necessary desaturase enzymes may not be able
to function properly. [14]
Flavonoids
Flavonoids are compounds that
function (among other things) in
plants to prevent damage from
excessive sun exposure. When
ingested, flavonoids
compounds act to "quench" reactive
oxygen species that have the
capacity to damage cellular
structures, such as membranes and
DNA. Flavonoids have demonstrated
a number of effects within the human
body including; assisting the reduction
of capillary
permeability and fragility,
and specific anti-viral and anti-inflammatory
properties. Flavonoids
help to reduce damage that
free radicals can cause as well as
reducing the intensity of allergic
reactions. [15]
Herbal Treatments:
Licorice root (Glycerrhiza
glabra)
Licorice root (Glycerrhiza
glabra) is a botanical agent
that appears to be useful both
internally and topically in
patients with atopic dermatitis. Patients reported better sleep and
less itching in studies using
licorice. [16] Licorice exerts cortisol sparing
effects by inhibiting the enzymes
that are responsible for cortisol
metabolism. Cortisol is a natural anti-inflammatory
compound within the body. By
sparring cortisol, licorice
root's anti
inflammatory action can be
heightened without having to use
synthetic hydrocortisone
compounds. [17]
Topical applications of Glycyrrhetic acid from licorice have resulted in significant
improvements in eczema symptoms.
Effects are
comparable to that of
hydrocortisone cream, but are less
likely to have some of the same
side effects that can be observed
in the use of pharmaceutical
hydrocortisone cream.
Chamomile (Matricaria recutita)
Chamomile has shown promise in
specific
treatments of eczema. Chamomile is
known for having
anti-inflammatory, wound healing, anxiolytic, anti microbial, and
antispasmodic properties.
This herb can be used both
topically and internally to
address some of the possible
complications that are inherent in
cases of atopic dermatitis. An
extract of chamomile has been
shown to have benefits superior to
that of 0.5% hydrocortisone cream
in treating the symptoms of atopic
dermatitis. It was also
shown to promote the
formation of granulation tissue; a
tissue vital for proper wound healing. [19]
Another use for chamomile in
eczema sufferers may be anxiety-related
conditions. Anxiety is a common
psychological condition among
patients with this skin disease.
The anxiolytic and calming effects
of chamomile may help to ameliorate
feelings of tension and anxiety,
which can come from the itching and
discomfort of eczema. [20]