The study, published in the journal Cancer (2005, vol. 103, no. 5), investigated the association between PSA and body mass index (BMI) in men without prostate cancer. Researchers at the University of Texas Health Science Center in San Antonio analyzed the data of 2,779 men without prostate cancer participating in a study sponsored by the San Antonio Center of Biomarkers of Risk, between 2001 and 2004. Serum PSA and BMI measurements were obtained from the participants.
Researchers found that obese participants had lower PSA levels than normal weight participants. The PSA values ranged from 0.69 ng/mL in obese men to 1.01 ng/mL in normal weight men. These study results suggest that the PSA test may be less accurate in obese men. "Lower levels of PSA in obese and overweight men could mask biologically consequential prostate carcinoma," the study authors conclude.
Posted by Kristopher Foster on May 12, 2006 04:08 PM
