Omega-3 fatty acids have been touted for many disorders, primarily linked to their ability to influence inflammatory conditions. Omega-3 fatty acids are found in significant amounts in cold-water fish like salmon, mackerel and cod. Research presented at the International Academy of Nutrition & Aging 2006 SYMPOSIUM II on May 2, 2006, in Chicago by Richard Wurtman, Distinguished Professor of Neuropharmacology at MIT, examined the effects of omega-3s on the cell membranes that form nerve synapses in the brain. Researchers fed gerbils a combination of three natural occurring body chemicals, omega-3 fatty acids, uridine and choline, which make up phospholipids, the primary component of cell membranes in the brain. The results showed that the animals had formed more brain synapses, which allow more messages to pass. The next step is human trials. Dr. Wurtman believes that if these results are duplicated in placebo-controlled human trials, then the effects of Alzheimer's may be ameliorated just like L-dopa can alleviate the symptoms of Parkinson's disease and slow its progression.
Prior work published in the American Journal of Clinical Nutrition (2005;82(2):281-295) reviewed the evidence and concluded that the bulk of research shows that increases in brain levels of DHA (an omega-3 fatty acid) are associated with improved cognitive or behavioral function.
When choosing an omega-3 supplement, all products are not created equally. Because these supplements are fat, they can become rancid. As well, most products are purified from fish oil and may be contaminated with PCBs and heavy metals, like mercury. High quality supplements will be tested for such components and rancidity will be prevented in processing.
Posted by Dr. Jennifer Stagg on June 30, 2006 05:21 PM
