The in vivo study, published in Cancer Research (2006, vol 66, no 2), investigated the anticancer effects of curcumin and PEITC, alone or in combination. Researchers at Rutgers' Ernest Mario School of Pharmacy in New Jersey injected curcumin or PEITC, either alone or in combination, into specially bred mice three times a week for one month. The mice were implanted with human prostate cancer cells on the second day of treatment.
The researchers found that curcumin and PEITC reduced tumor growth, and the combination of both nutrients were even more effective. Findings also revealed that curcumin and PEITC together significantly reduced the growth of established late stage tumors. However, curcumin and PEITC administered alone did not effectively retard the growth of established tumors. This suggests that curcumin and PEITC alone may be effective for cancer prevention but not for established tumors.
"Taken together, our results show that PEITC and curcumin alone or in combination possess significant cancer-preventive activities in the PC-3 prostate tumor xenografts," the study authors write. "Furthermore, we found that combination of PEITC and curcumin could be effective in the cancer-therapeutic treatment of prostate cancers."
Posted by Kristopher Foster on May 6, 2006 07:30 PM
