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During digestion, the
lower esophageal sphincter (the
valve that separates the esophagus
and stomach) opens to allow food to
pass into the stomach, and then
closes to prevent the stomach
contents from flowing back up.
However,
acid reflux occurs when
the lower esophageal sphincter
inappropriately opens, allowing
the gastric contents to back up. This leads to a burning pain or
discomfort in the upper abdomen and
chest, known as heartburn. Acid reflux
can be caused by the following
dietary sources and conditions:
Other causes may
include hiatal hernia (an
outpouching of the stomach above the
diaphragm), ulcer disease, and
gastritis (inflammation of the
stomach). These factors either
increase abdominal pressure or cause
the esophageal sphincter to
inappropriately relax, allowing the
stomach contents to back up.
If acid reflux remains untreated
over time, it can cause scarring
and precancerous changes of the
esophagus (Barrett's syndrome), and
an increased risk for the
development of esophageal cancer.
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