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Migraine Headache Introduction

 

Migraine headaches are recurrent episodes of head pain.  These particular headaches are characterized by pulsatile and unilateral pain, long durations, and are often associate with nausea, vomiting, and/or a sensitivity to light (photophobia). [1

 

It is theorized that migraine headaches are caused by the vasodilation of the blood vessels in the head.  Although its exact mechanism of action is unknown, platelet aggregation, serotonin metabolism, inflammatory prostaglandins, and histamine production are all thought to play a role in the development of this condition. [2]

 

Migraines can be classified into three types: common, classic, and complicated. 

  • Common migraines: account for 80% of migraines, last 1-3 days, have frontal and one-sided pain, and no other symptoms.
     

  • Classic migraines: account for nearly 10% of all cases, last 2-6 hours, are unilateral, have an aura, and may present with nausea, vomiting, and pallor. 
     

  • Complicated migraines: account for 10% of cases also, last for an extended period of time, pain can be present anywhere and may even be absent. Additionally, there is an aura, vertigo, faintness, and mild neurological impairment, such as temporary loss of speech and paralysis. [3]

 

Migraine Symptoms and Statistics

 

Migraines may be preceded by a prodromal period of depression, anorexia, irritability, and restlessness.  10-20% of migraines also present with conditions caused by prodromal auras.  An aura is an irreversible change in vision, motor, or language skills perceived by the patient and others.  The aura usually appears 1 hour before the onset of the migraine.

 

Migraines usually follow a pattern, but can present on different sides of the head. Attacks can be a daily occurrence or be sporadic in nature, only affecting persons 3-4 times per year.  Pain is described as a throbbing or pounding sensation that can last from hours to days. [4]

 

Besides pain, individuals with migraines may be subject to nausea and vomiting.  They may also experience vertigo (dizziness), fainting, double vision, and numbness or tingling in a limb.  In extreme cases, individuals can have speech deficits, limb paralysis, and palsy's of the cranial nerve III. [5]

 

Migraine Statistics:

  • It is estimated that 28 million Americans suffer from migraines.  This equates to 1 in 9 persons suffering from a specific form of migraine headache;  or 1 out of every 4 households..
     

  • It is also estimated that as many as 14 million cases of migraine remain undiagnosed.  75% of individuals ( 21 million) suffering from migraines are women. [6]
     

  • The most common ages of occurrence are between 10 and 40, while most migraines usually resolving by age 50.  This fact may be, in large part, due to menopause in women (with women being the largest group affected).  50% of individuals with migraines have a strong family history of the condition. [7]

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